Pde5 Inhibitor

Tadalafil 25mg


Active Ingredient:Tadalafil

Tablet Count: 50 Tablets

Half-Life: 17.5 Hours

Classification: Pde5 Inhibitor

Dosage: 5-20 mg as needed

Acne: None

Water Retention: Low

Hepatotoxicity: Low

Aromatization: None


Cialis, with Tadalafil as its active ingredient, is a highly regarded prescription medication in the realm of male health. Renowned for its effectiveness in treating erectile dysfunction (ED) and benign prostatic hyperplasia (BPH), Cialis has become a cornerstone for those seeking improved sexual performance and relief from prostate-related symptoms. Bodybuilders and athletes also appreciate Cialis for its ability to support overall well-being and recovery, though it is primarily used for its approved medical indications.


Mechanism of Action:

Cialis works by inhibiting the enzyme phosphodiesterase type 5 (PDE5), which plays a crucial role in regulating blood flow. PDE5 breaks down cyclic guanosine monophosphate (cGMP), a molecule responsible for relaxing the smooth muscles and dilating blood vessels in the penis. By preventing this breakdown, Cialis ensures that cGMP remains active, allowing for enhanced blood flow and sustained erections. Additionally, Tadalafil’s effects extend to reducing tension in blood vessels and improving overall circulation, which contributes to its benefits for both ED and BPH.


Metabolism of Tadalafil

Tadalafil is metabolized primarily in the liver through the CYP3A4 enzyme system. This process is essential for breaking down the compound and ensuring its effective elimination from the body. Understanding Tadalafil’s metabolic pathway is crucial for determining appropriate dosages and avoiding potential interactions with other medications processed by the same enzyme system. Regular monitoring of liver function is recommended to ensure safe and effective use.


Usage and Dosage

Cialis is available in various strengths, including 2.5 mg, 5mg, 10 mg, and 20 mg tablets. For erectile dysfunction, the medication can be taken as needed, approximately 30 minutes before sexual activity, with effects lasting up to 36 hours. Alternatively, a daily low-dose regimen (2.5 mg or 5 mg) can be used for continuous treatment of ED. For benign prostatic hyperplasia, a daily dose of 5 mg is typically prescribed. It is important to consult with a healthcare provider to determine the most appropriate dosage based on individual needs and medical conditions.

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