Cardarine is the popular name for the research drug GW- 501516, which embodies a remarkable compound initially designed by Ligand Pharmaceuticals and GlaxoSmithKline in the 1990s. This compound was developed to bring a drug to market that could guard against metabolic and cardiovascular diseases.

As stated earlier in this book, while Cardarine is lumped in the same category as SARMs (selective androgen receptor modulators), it has no effects on the Androgen Receptor, so it is not a SARM; in actuality, it is a PPARδ (Peroxisome Proliferator-Activated Receptor delta) agonist. We’ll talk about this a bit later.

What can you expect from using Cardarine (GW-501516)?

-Fat loss
-Endurance increase (Cardio boost)
-Cholesterol improvements

Therapeutic Aims and Benefits

Initially, the development of GW-501516 was aimed at treating the following health conditions:

Obesity: By targeting fat stores and enhancing metabolic activity.
Diabetes: Through the modulation of metabolic pathways.
Lipid Strain: By positively influencing cholesterol levels.
Cardiovascular Diseases: Through its impact on lipid profiles and energy expenditure.

Fitness Benefits

Bodybuilding and fitness users have reported substantial improvements in cholesterol levels, with LDL/HDL leveling out after usage. Also, most users report significant gains in endurance during cardio. Some anecdotal evidence suggests a boost of 100% in cardio output by using Cardarine.

The biggest plus of GW-501516 is the fat loss, and many users report “body fat melting off” as they use Cardarine.

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