NSI-189 Phosphate

NSI-189 PHOSPHATE POWDER / NSI-189 PHOSPHATE 30ML LIQUID


Overview: NSI-189 Phosphate is a novel nootropic and neurogenic compound originally developed as a potential treatment for major depressive disorder (MDD) and cognitive impairment. This synthetic molecule is derived from nicotinamide (a form of vitamin B3) and pyrazine, and it stands out for its unique ability to stimulate neurogenesis—the growth of new neurons—in the hippocampus, a region of the brain crucial for memory, learning, and emotional regulation. Beyond its potential therapeutic applications, NSI-189 Phosphate has gained attention in the nootropic community for its ability to enhance mood, improve cognitive function, and support overall brain health.


Mechanism of Action: NSI-189 Phosphate works by promoting the growth of new neurons and increasing synaptic plasticity in the hippocampus, which is essential for learning, memory, and mood regulation. While the exact mechanism of action is still being studied, it is believed that NSI-189 Phosphate activates pathways involved in neurogenesis, leading to an increase in the size and function of the hippocampus. This neurogenic effect not only supports cognitive function but also has a positive impact on mood, potentially alleviating symptoms of depression and anxiety. Additionally, NSI-189 Phosphate has been shown to enhance overall brain function by improving glucose metabolism and reducing oxidative stress in neural tissues.


Benefits:

Enhanced Memory and Learning: By stimulating neurogenesis and increasing hippocampal volume, NSI-189 Phosphate enhances memory formation, retention, and recall. This makes it particularly valuable for individuals looking to improve their cognitive abilities, especially in areas related to learning and information processing.

Mood Improvement: NSI-189 Phosphate is known for its antidepressant and anxiolytic effects, helping to stabilize mood and reduce symptoms of depression and anxiety. Its ability to promote neurogenesis in the hippocampus, a region often compromised in depression, is a key factor in its moodenhancing properties.

Cognitive Enhancement: In addition to improving memory and mood, NSI-189 Phosphate enhances overall cognitive function, including focus, mental clarity, and problem-solving abilities. This makes it a powerful tool for anyone seeking to boost their mental performance.

Neuroprotection: NSI-189 Phosphate’s ability to promote neurogenesis and reduce oxidative stress supports long-term brain health, potentially protecting against cognitive decline and neurodegenerative conditions.


Usage and Dosage: The typical dosage of NSI-189 Phosphate ranges from 20 to 40 mg per day, often divided into two doses, taken in the morning and early afternoon. It’s recommended to start with the lower end of the dosage range to assess tolerance and gradually increase as needed. NSI-189 Phosphate can be taken with or without food, and consistent use over several weeks is generally required to fully experience its cognitive and mood-enhancing effects. Due to its potent neurogenic effects, cycling NSI-189 Phosphate may not be necessary, but periodic breaks can be beneficial to prevent receptor desensitization.


Side Effects and Considerations: NSI-189 Phosphate is generally well-tolerated, with few reported side effects. However, some users may experience mild symptoms such as headaches, dizziness, or fatigue, particularly when first starting the supplement or at higher doses. Because NSI189 Phosphate is still under investigation for its full range of effects, it’s important to approach its use with caution and to consult with a healthcare provider before starting, especially if you have underlying health conditions or are taking other medications. Pregnant or nursing women should avoid using NSI-189 Phosphate due to the lack of safety data.


For more details, visit the Umbrella Labs product page.