S-23 is a true Selective Androgen Receptor Modulator (SARM). It was developed for therapeutic applications, mainly as a male hormonal contraceptive. It is one of the newer SARM compounds available on the market only a few short years ago.


Proposed Benefits

Muscle Mass Enhancement: S-23 can increase lean muscle mass and enhance endurance.

Androgen Receptor Binding: S-23 has a very high affinity for binding to the androgen receptor. Way higher than RAD-140 or LGD-4033.

Fat Reduction: Many users have a drop in body fat during S-23 cycles.

Bone Health: S-23, in some anecdotal investigations, helps bone health, making stronger joints.


Mechanism of Action

S-23, like other SARMs, is believed to selectively bind to androgen receptors in muscle and bone tissues, ostensibly promoting increased muscle mass and bone density by stimulating anabolic activity in these tissues. The notion behind SARMs is that this selectivity allows for beneficial androgenic effects in targeted tissues without invokingundesired side effects typically seen with anabolic androgenic steroids.

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Dosage and Cycle Protocols

Anecdotally, we see the dose of 10mg to 30mg per day. We would have most guys start with 10mgs.


Potential Side Effects

S-23 suppresses testosterone levels, there is no doubt. There are reports of significant testosterone suppression and impact on other sex hormones. This is proven via blood work.

Altered Lipid Profiles: Users have reported experiencing bloating and mild edema, just like HGH injections.

Mood Alterations: Some users report experiencing mood.


“S23 may be the strongest SARM in existence, so keep in mind that it requires a full Post-Cycle Therapy protocol as opposed to a standard mini PCT.”

-Dylan Gemelli

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