IGF-1 LR3

IGF-1 LR3, or Insulin-like Growth Factor 1 Long R3, is a modified version of the naturally occurring IGF-1 hormone. This hormone plays a vital role in childhood growth and continues to have anabolic effects in adults. The “LR3” version is a longeracting variant designed to significantly increase the biological activity and stability of IGF-1, making it a powerful tool for muscle building, performance enhancement, and recovery.


Mechanism of Action

IGF-1 LR3 exerts its effects by binding to the IGF-1 receptor, which is present in many cell types throughout the body. It has a higher affinity for this receptor than regular IGF-1 due to its resistance to binding proteins that usually inhibit the biological actions of IGF-1. By activating the IGF-1 receptor, IGF-1 LR3 stimulates cell growth (hypertrophy) and differentiation and prevents cell death. It enhances amino acid uptake and protein synthesis in muscle tissues, increasing muscle growth and repair. Additionally, IGF-1 LR3 can influence fat metabolism, promoting fat loss.


Benefits and Uses

Muscle Growth and Recovery: Significantly promotes muscle hypertrophy and accelerates recovery from intense physical training.

Increased Strength: Enhances strength gains alongside muscle growth.

Fat Loss: Aids in body recomposition by improving fat metabolism, contributing to a leaner physique.

Improved Performance: Users may experience enhanced overall athletic performance.

Anti-Aging Properties: Potential benefits include improvedskin appearance, increased energy levels, and overall vitality due to its cell growth-promoting properties.

IGF-1 LR3’s diverse benefits make it popular among bodybuilders, athletes, and those seeking anti-aging solutions.


Dosage and Cycle Guidelines

A typical dosage of IGF-1 LR3 ranges from 20 to 100 mcg per day, depending on individual goals, experience, and tolerance. The peptide is administered via subcutaneous or intramuscular injections to utilize its muscle repair and growth capabilities, preferably post-workout. Cycle lengths are typically 4-6 weeks to prevent the body from adapting and reducing the peptide’s effectiveness. Following a cycle, a break period equal to the cycle length is recommended to allow the body to reset.


Potential Side Effects

Hypoglycemia: The most significant risk is a drop in blood sugar levels, which can lead to symptoms of hypoglycemia.

Acromegaly: Long-term overuse can lead to abnormal growth of bones and tissues.

Increased Tumor Growth: There’s a theoretical risk of promoting the growth of pre-existing cancerous cells due to its cell proliferation effects.

Pain at Injection Site: Common with injectables, some may experience discomfort or bruising.

Water Retention and Swelling: Some users report edema and water retention, particularly in extremities.

Given its potent effects, careful dosage, cycle length, and side effects monitoring is crucial when using IGF-1 LR3. It’s advisable to consult with a healthcare professional before starting any new peptide regimen, especially for individuals with pre-existing medical conditions or those new to peptide use.