Anadrol, also known as Oxymetholone, is well known in the bodybuilding community as one of the most potent oral anabolic steroids available, renowned for its remarkable ability to facilitate rapid and significant muscle mass and strength gains. This perception often places Anadrol in high regard among serious bodybuilders and strength athletes, especially those looking for dramatic improvements in a short time. However, this potency comes with a reputation for equally significant side effects, including notable water retention, increased risk of liver toxicity, and pronounced effects such as gynecomastia. Due to these potential adverse effects, Anadrol is often approached with caution and respect. Users typically reserve it for bulking phases and view it as a powerful tool for overcoming plateaus in muscle growth. Despite its efficacy in muscle building, the bodybuilding community generally advises against its use by beginners or those less experienced with managing the side effects of strong androgens. Here’s an overview of how it’s used:

Rapid Mass Gain: Anadrol is renowned for its ability to promote rapid gains in muscle mass and strength, making it a favorite for bulking cycles.

Water Retention: One of its characteristics is significant water retention, contributing to the rapid increase in strength, size, and weight.


History of Anadrol (Oxymetholone)

Anadrol was first developed in the late 1950s by Syntex Pharmaceuticals. Initially prescribed in 1959, its early use was aimed at treating medical conditions such as anemia and osteoporosis due to its effectiveness in increasing red blood cell production. The development of Anadrol was primarily motivated by the need for a potent anabolic agent that could that could address these conditions. Despite its efficacy, Anadrol was discontinued shortly after its introduction in 1961 due to concerns about its high lipid toxicity.

However, its powerful anabolic properties quickly gained the attention of the bodybuilding and athletic communities. Anadrol became renowned for its ability to promote significant muscle mass and strength gains, making it a popular choice among competitive athletes and bodybuilders. By the 1970s, it had established itself as a potent performanceenhancing drug. In the 1990s, Anadrol’s medical application saw a resurgence when it was discovered to be effective in treating HIV/AIDS wasting syndrome, bringing it back to the pharmaceutical market. This period marked a new chapter in the drug’s history, as it balanced its role between a therapeutic agent and a performance enhancer.

Anadrol has been regulated, and it has been classified as a controlled substance in many countries, making its nonmedical use generally illicit. Despite being discontinued in the U.S. market, Anadrol retains FDA approval, though its production and distribution have become more regulated.

Anadrol is not commonly available through standard channels in the contemporary pharmaceutical landscape. Its availability is mostly through specialized avenues, such as compounding pharmacies under specific medical circumstances, adhering to the legal frameworks that distinguish between approved drugs and compounded medications.


Here is a list of diseases for which Anadrol has been prescribed:

Treatment of Anemia: Anadrol was initially used to treat various forms of anemia, as it was found to be highly effective in increasing red blood cell production.

Osteoporosis and Muscle Wasting Diseases: Beyond anemia, it was also prescribed for conditions like osteoporosis and muscle wasting diseases due to its strong anabolic properties.

HIV/AIDS Wasting Syndrome: Later on, it found use in treating HIV/AIDS wasting syndrome, helping patients maintain muscle mass and body weight.


Prescription, Bodybuilding and Powerlifting Dosage Guidelines

General Medical Use: The recommended daily dose in children and adults is 1-5 mg/kg of body weight per day. The usual effective dose is 1-2 mg/kg/day, but higher doses may be required, and the dose should be individualized. The response is not often immediate, and a minimum trial of three to six months is usually necessary.

Beginner Users

  • Anadrol can be considered a more advanced steroid, so beginners are advised to start with milder steroids first, like Anavar.
  • A common starting dose is 50mg per day, which can be split into two to three doses daily.
  • 25mg per day can often be enough, especially for first-time users, and will cause fewer side effects.

Intermediate Users

  • Intermediate users typically use Anadrol at 50mg to 100mg daily.
  • It is often used in a stack with injectable testosterone for bulking, with Anadrol at 50mg weekly for 4-6 weeks and testosterone at 500mg weekly for 12 weeks.

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