MGF, or Mechano Growth Factor, is a splice variant of IGF1 (Insulin-like Growth Factor 1) produced by muscle tissues in response to mechanical overload or damage. It plays a crucial role in muscle growth and repair by activating satellite cells, contributing to the development of new muscle fibers, and the restoration of damaged ones.

Mechanism of Action

MGF is unique because it’s activated by mechanical stimuli, such as resistance training or muscle damage. Upon activation, MGF initiates the upregulation of protein synthesis, leading to muscle growth and repair. It does this by activating muscle stem cells or satellite cells, prompting them to enter the cell cycle and differentiate into new muscle fibers. Additionally, MGF stimulates the uptake of amino acids into the muscle cells, further aiding in muscle growth and repair.

Benefits and Uses

Enhanced Muscle Growth: By stimulating satellite cells, MGF promotes the growth of new muscle fibers, contributing to increased muscle mass.

Improved Muscle Repair: MGF plays a significant role in the repair and recovery of muscle tissues damaged during intense physical activity.

Rapid Recovery from Injury: Its regenerative properties extend to accelerating the healing process of muscle injuries.

Potential Anti-Aging Effects: Through its muscle regeneration capabilities, MGF may also help counteract the loss of muscle mass associated with aging

MGF’s targeted approach to muscle growth and repair makes it particularly appealing for athletes, bodybuilders, and those recovering from muscle-related injuries.